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DBSP Graduate Students

Dan Qiao

Dan Qiao

PhD Candidate, Virology
Department of Biomedical Sciences & Pathobiology
Graduate Advisor: Dr. Elankumaron Subbiah

e-mail: qiao@vt.edu


Education

2001-2006 Bachelor of Agriculture, DVM
College of Veterinary Medicine
China Agricultural University
Beijing, China
2006-present PhD Program, Biomedical & Veterinary Sciences
Virginia-Maryland Regional College of Veterinary Medicine
Center for Molecular Medicine & Infectious Diseases
Virginia Polytechnic Institute and State University
Blacksburg, VA, USA

Brief Bio

My current research is focused on a novel swine paramyxovirus molecular and pathogenic characterization and develops it into vaccine vector for other pathogens. I love outdoor activities such as hiking, rafting and ski, and I love watching movie in my spare time. I love animals especially the wildlife animals. Chimpanzees and dolphins are my favorite.


Research Project Involvement

  • Reverse Genetic system of a novel Swine Paramyxovirus
    Two novel swine paramyxovirus viruses were isolated from the pigs experienced respiratory and neurological symptoms. We initiate the molecular and pathogenic characterization of the novel swine paramyxoviruses and try to establish a reverse genetic system. We will use the reverse genetic system to rescue recombinant virus engineered by molecular biology technique and use it as vaccine for other pathogens.
  • Protease activation mutants Newcastle Disease Virus
    Newcastle Disease Virus(NDV) is a naturally oncolytic virus. By changing the F cleavage site of the fusion glycoprotein of NDV, the site becomes susceptible to MMPs(Matrix metalloproteinases), a group of protease that are highly expressed in tumor cells but not in normal cells. These recombinant viruses rescued from NDV reverse genetic system will require specific protease to replicate and spread which will be only present in tumor cells and by this way, these viruses can be used in cancer theropy.

Professional Experience

Aug 2006-present PhD Graduate Student
Center for Molecular Medicine & Infectious Diseases
Blacksburg, VA, USA
Sept 2005-Jun 2006 Research Assistant
Center of Molecular Virology
The Institute of Microbiology
Chinese Academy of Sciences
Beijing, China
Jun 2005-Sept 2005 Research Assistant
Key laboratory of preventive Veterinary Medicine
China Agricultural University
Beijing, China

Professional Memberships

  • American Society for Virology